Kerala PSC Pharmacist Gr II Mock 010

Q1.Which among the following factors is NOT a primary consideration for selecting an appropriate container for a sterile ophthalmic solution?

Q2.A pharmacist is preparing a batch of intravenous injections. Which of the following sterilization methods is most suitable for heat-sensitive drugs?

Q3.Which type of glass is preferred for packaging parenteral solutions due to its high hydrolytic resistance and low alkali content?

Q4.The stability of a suspension formulation is primarily affected by which of the following factors?

Q5.Which of the following excipients is commonly used in the preparation of effervescent tablets to aid in rapid disintegration and dissolution?

Q6.A pharmacist observes that a batch of soft gelatin capsules has developed a sticky texture after storage. Which of the following is the most likely cause?

Q7.Which of the following packaging materials is most suitable for a light-sensitive drug like nitroglycerin?

Q8.The 'beyond-use date' for a compounded sterile product is typically determined based on which of the following factors?

Q9.Which type of tablet coating is most commonly used to mask the bitter taste of drugs and improve patient compliance?

Q10.A pharmacist is preparing a topical ointment and wants to ensure uniform distribution of the active ingredient. Which of the following techniques is most appropriate?

Q11.Which of the following functional groups is primarily responsible for the acidic properties of aspirin (acetylsalicylic acid)?

Q12.Paracetamol (acetaminophen) is metabolized primarily in the liver to form an active metabolite. Which of the following describes the correct metabolic pathway?

Q13.Which of the following inorganic compounds is commonly used as an antacid due to its ability to neutralize stomach acid?

Q14.Which of the following vitamins is a cofactor for the carboxylation reactions involved in the synthesis of clotting factors like prothrombin?

Q15.Which of the following drugs is a selective serotonin reuptake inhibitor (SSRI) used primarily as an antidepressant?

Q16.Which of the following functional groups is characteristic of local anesthetics like lidocaine?

Q17.Which of the following is a key enzyme involved in the synthesis of cholesterol, making it a target for statin drugs?

Q18.Which of the following compounds is a common ingredient in oral rehydration solutions (ORS) used to treat dehydration?

Q19.Which of the following is a characteristic of non-electrolytes in solution?

Q20.Which of the following is a common side effect of prolonged use of proton pump inhibitors (PPIs) like omeprazole?

Q21.A 55-year-old male with hypertension and type 2 diabetes mellitus is prescribed lisinopril for blood pressure control. Which of the following laboratory parameters should be monitored closely during the initial phase of therapy?

Q22.A patient on long-term warfarin therapy develops bleeding gums and prolonged epistaxis. Which of the following drug classes is most likely to exacerbate this bleeding risk when combined with warfarin?

Q23.A patient with chronic obstructive pulmonary disease (COPD) is prescribed theophylline for bronchodilation. Which of the following adverse effects is most commonly associated with theophylline toxicity?

Q24.A 30-year-old female with a history of epilepsy is stabilized on phenytoin. She is now diagnosed with a urinary tract infection and prescribed cotrimoxazole. Which of the following is a potential drug interaction between phenytoin and cotrimoxazole?

Q25.A patient with congestive heart failure is prescribed digoxin for inotropic support. Which of the following electrolyte abnormalities is most likely to precipitate digoxin toxicity?

Q26.A 45-year-old male with schizophrenia is started on haloperidol. After 2 weeks, he develops restlessness, pacing, and an inability to sit still. Which of the following adverse drug reactions is most likely responsible?

Q27.A patient with rheumatoid arthritis is prescribed methotrexate. Which of the following laboratory tests should be monitored regularly to detect early signs of methotrexate toxicity?

Q28.A 60-year-old male with hypertension is prescribed amlodipine. He reports ankle swelling and peripheral edema after starting the medication. Which of the following is the most likely mechanism for this adverse effect?

Q29.A patient with bipolar disorder is stabilized on lithium carbonate. The patient's serum lithium levels are found to be 1.8 mEq/L. Which of the following symptoms is most likely to manifest at this level?

Q30.A patient with type 2 diabetes mellitus is prescribed metformin. Which of the following drug classes, when combined with metformin, increases the risk of lactic acidosis?

Q31.Which of the following crude drugs contains the alkaloid 'hyoscyamine' as its primary active constituent?

Q32.The glycoside 'digitoxin' is primarily obtained from which of the following plants?

Q33.Which crude drug is commonly used in Ayurveda for its anti-inflammatory and antipyretic properties and contains the glycoside 'salicin'?

Q34.The alkaloid 'quinine' is primarily derived from which plant source?

Q35.Which of the following drugs is a cardiac glycoside used in the treatment of congestive heart failure and is obtained from Digitalis lanata?

Q36.The glycoside 'aloe-emodin' is primarily found in which of the following crude drugs?

Q37.Which crude drug is known for its use in treating malaria and contains the alkaloid 'quinidine'?

Q38.The glycoside 'sennoside' is primarily obtained from which of the following plants?

Q39.Which of the following alkaloids is known for its use in treating Alzheimer's disease and is obtained from the plant Huperzia serrata?

Q40.The crude drug 'Opium' is obtained from which part of the Papaver somniferum plant?

Q41.In a hospital pharmacy setting, which method of drug distribution is most suitable for managing controlled substances like opioids to ensure accountability and reduce diversion?

Q42.A pharmacist in the IPD pharmacy receives an order for IV Vancomycin 1g to be administered over 2 hours. The available vial contains 500 mg of Vancomycin. How many vials should the pharmacist use to prepare the prescribed dose?

Q43.Which of the following is the primary advantage of a decentralized pharmacy service model in a hospital?

Q44.A patient in the oncology ward is prescribed a chemotherapy drug that must be prepared in a sterile laminar airflow hood. Which of the following is the MOST critical step in ensuring sterility during compounding?

Q45.In a hospital OPD pharmacy, which of the following actions is essential when dispensing a prescription for a pediatric patient?

Q46.A pharmacist in the IPD pharmacy notices that a patient's IV line has become disconnected, and the prescribed antibiotic is leaking onto the bed. What is the FIRST action the pharmacist should take?

Q47.Which of the following is the MOST appropriate method for storing insulin in a hospital pharmacy to maintain its potency?

Q48.A hospital pharmacy uses a barcode medication administration (BCMA) system. Which of the following is the PRIMARY benefit of this system?

Q49.In a sterile compounding area, which of the following is the CORRECT order for donning personal protective equipment (PPE)?

Q50.A pharmacist in the OPD pharmacy receives a prescription for a patient with chronic kidney disease. Which of the following actions is MOST important before dispensing the medication?

Q51.Under the Narcotic Drugs and Psychotropic Substances (NDPS) Act, 1985, which authority is empowered to issue licenses for the manufacture, sale, or export of narcotic drugs?

Q52.Which schedule of the Drugs and Cosmetics Act, 1940, includes drugs that are habit-forming and listed under the NDPS Act?

Q53.A pharmacist receives a prescription for a Schedule H drug. How many times can this prescription be refilled without a fresh prescription?

Q54.Under the Pharmacy Act, 1948, which of the following is NOT a requirement for obtaining a pharmacist license?

Q55.Which authority is responsible for the enforcement of the Narcotic Drugs and Psychotropic Substances (NDPS) Act at the state level?

Q56.A pharmacy owner wants to stock and dispense a new injectable opioid analgesic. Which schedule under the Drugs and Cosmetics Act must the drug be listed in for legal dispensing?

Q57.Which of the following is NOT a function of the State Pharmacy Council under the Pharmacy Act, 1948?

Q58.A patient presents a prescription for a drug containing 10 mg of morphine. The pharmacist notices the prescription is issued by a registered medical practitioner but lacks the required 'R' mark. What should the pharmacist do?

Q59.Under the NDPS Act, what is the minimum quantity of cocaine that triggers the offense of 'small quantity' for personal use?

Q60.A pharmacy student asks their preceptor about the legal status of selling codeine-containing cough syrups over the counter. Which schedule under the Drugs and Cosmetics Act governs the sale of such preparations?

Q61.Which of the following structures is primarily responsible for the regulation of body temperature?

Q62.A patient with chronic kidney disease (CKD) is advised to restrict dietary intake of potassium. Which of the following electrolyte imbalances is most likely to occur if this restriction is not followed?

Q63.Which part of the respiratory system is responsible for the exchange of oxygen and carbon dioxide between the air and the blood?

Q64.Which of the following is the primary function of the liver in drug metabolism?

Q65.A patient with diabetes mellitus is advised to monitor their blood glucose levels regularly. Which endocrine organ's dysfunction is responsible for diabetes mellitus?

Q66.Which of the following is a correct statement about the role of the kidney in maintaining acid-base balance?

Q67.A pharmacist needs to educate a patient about the importance of dietary fiber. Which of the following is the primary benefit of dietary fiber in the digestive system?

Q68.Which of the following hormones is responsible for the 'fight or flight' response in the body?

Q69.A patient with hypertension is prescribed a diuretic. Which of the following electrolytes is most likely to be depleted due to the action of this drug?

Q70.Which of the following best describes the primary physiological function of the alveoli in the respiratory system?

Q71.Which of the following is the PRIMARY purpose of maintaining a 'daily cash register' in a drug store?

Q72.A pharmacist notices that a customer frequently requests a specific brand of painkiller without a prescription. What is the MOST appropriate first step?

Q73.Which inventory management system uses the 'First In, First Out' (FIFO) principle to minimize drug expiration?

Q74.A drug store owner wants to expand services by adding a 'Home Delivery' system. Which legal requirement must be prioritized FIRST?

Q75.Which of the following is a KEY advantage of 'Computerized Prescription Order Entry (CPOE)' in a drug store?

Q76.A medicine with an MRP of ₹100 is sold at a 10% discount. If the pharmacy’s profit margin is 20% on the selling price, what is the pharmacy’s cost price?

Q77.Which document is MANDATORY to maintain for controlled substances (e.g., morphine) in a drug store?

Q78.A customer requests a refill of a prescription without the original copy. The pharmacist should:

Q79.Which of the following is a CRITICAL factor in selecting a 'supplier' for a drug store?

Q80.In a drug store, which method is used to calculate the 'reorder level' of a fast-moving item like paracetamol?

Q81.Which of the following is the primary buffer system in the blood that helps maintain physiological pH?

Q82.A patient presents with symptoms of metabolic acidosis. Which laboratory finding would be most consistent with this condition?

Q83.Which enzyme is most commonly elevated in liver damage and is widely used as a marker for hepatocellular injury?

Q84.A patient's blood glucose level is 250 mg/dL. Which of the following laboratory tests would be most appropriate to assess long-term glucose control in this patient?

Q85.Which of the following conditions is most likely associated with an elevated serum creatinine level?

Q86.A 45-year-old male presents with fatigue and yellow discoloration of the skin. Laboratory findings show elevated total bilirubin and direct bilirubin. Which of the following is the most likely cause?

Q87.Which of the following is the primary site for the synthesis of ketone bodies in the body?

Q88.A patient with type 2 diabetes mellitus is prescribed metformin. Which of the following biochemical parameters should be monitored regularly to assess for potential adverse effects?

Q89.Which of the following laboratory findings is most indicative of a patient with an acute myocardial infarction (MI)?

Q90.A patient's lipid profile shows a total cholesterol of 240 mg/dL, LDL of 160 mg/dL, HDL of 30 mg/dL, and triglycerides of 200 mg/dL. Which of the following is the most appropriate next step?

Q91.The 'Kerala State Film Award for Best Actor' is awarded by which organization?

Q92.Which of the following awards is NOT directly associated with the field of literature in Kerala?

Q93.Under the 'Ayushman Bharat - Arogya Karnataka' scheme, which of the following services is NOT covered for eligible beneficiaries in Kerala?

Q94.The 'Kazhinja' scheme launched by the Kerala government focuses on which of the following health objectives?

Q95.Which of the following was the first indigenously developed COVID-19 vaccine in India, manufactured by Bharat Biotech in collaboration with ICMR and NIV?

Q96.Which of the following is NOT a key objective of the National Health Policy 2017 of India?

Q97.Under the National Health Policy 2017, which initiative is primarily aimed at reducing out-of-pocket expenditure for healthcare?

Q98.Which schedule of the Drugs and Cosmetics Act, 1940, mandates the maintenance of a separate register for the sale of Schedule X drugs in a pharmacy?

Q99.Under the Drugs and Cosmetics Act, 1940, which authority is responsible for the approval of clinical trials in India?

Q100.As per recent Kerala health department reports, which of the following diseases was identified as a significant public health concern in the state during 2023 due to its rising cases and potential for outbreaks?